Apr 15, 2010

KAWASAKI DISEASE – CAUSES, SYMPTOMS AND TREATMENT METHODS



Kawasaki Disease is an sickness that involves the skin, mouth, and lymph nodes. The disease commonly begins with a feverishness insensitive to tylenol or Empirin which continues for at diminutive 7 – 10 days. Many but not every children amend a expanded Atlantic on the cervix which looks same an infection. Some researchers conceive it is an infection, others an autoimmune modify excited by an incident or danger to an environmental toxin. The disease is seen more ofttimes in the season and outflow seasons. Kawasaki disease, or mucocutaneous lymph convexity syndrome, is a disease of uncharted drive that most ofttimes (80% of the time) affects infants and children low fivesome eld of age. Some doctors conceive it haw be caused by a virus or a bacteria. The sickness crapper terminal from 2 weeks to a whatever months. Originally, KD was believed to be an acute, self-limiting symptom disease with an superior prognosis; however, ensuant reports indicated that nearly 2% of patients with KD died from the illness, commonly as a termination of alternative cardiac sequelae. It was prototypal detected in continent children mass World War II. No murder effort for Kawasaki disease is available. The identification is supported on symptoms.

Kawasaki disease is a poorly apprehended illness. The male-to-female ratio among patients with Kawasaki disease is 1.5:1. Children of nearly every interracial backgrounds are affected. Recurrences and cases in siblings are seen exclusive occasionally. The most essential conception of Kawasaki disease is its way to drive rousing of the thrombosis arteries which cater murder to the heart. Changes crapper be institute on echocardiogram in most 15% of patients. The rousing is uncomfortable, but resolves with time. However, the important danger from Kawasaki disease comes from its gist on the hunch and murder vessels. Affected children amend flushed eyes, flushed secretion membranes in the mouth, flushed unsmooth lips, a “strawberry tongue” and expanded lymph nodes. Skin rashes become primeval in the disease and shedding of the wound in the genital area, hands, and feet (especially around the nails and on the palms and soles) haw become in after phases. Kawasaki disease is a systemic vasculitis of uncharted drive that affects the small- and medium-sized murder vessels of the body, in particular, the thrombosis arteries. Early communication is trenchant in preventing this, but prototypal Kawasaki disease staleness be recognized.

Causes of Kawasaki disease

The ordinary causes and venture factor’s of Kawasaki disease allow the following:

The exect drive of Kawasaki Disease is unknown.

Abnormality of the insusceptible system.

Some doctors conceive it haw be caused by a virus or a bacteria. The sickness crapper terminal from 2 weeks to a whatever months.

Other researchers conceive that KD is caused by a unequalled bacterial toxin.

Several organisms hit been investigated as the doable cause agents, as follows: mite-associated bacteria, tick-borne diseases, bacterium species, Propionibacterium acnes, and individual viruses much as Epstein-Barr virus and retroviruses.

Additional venture factors in the United States allow continent vie and male.

A diminutive doable unification with furnishings shampoo or experience nearby a embody of adynamic water, but neither of these theories hit still been established.

Symptoms of Kawasaki disease

Some clew and symptoms attendant to Kawasaki disease are as follows:

Fever.

Swollen safekeeping and feet.

Diarrhea.

Vomiting.

Eye botheration (conjunctivitis) without pus.

Fretfulness.

Abdominal pain.

Palms of safekeeping and soles of feet are red; wound starts to peel soured fingers and toes most 2 weeks after sickness starts.

A expanded lymph convexity (“gland”) in the cervix area.

A flushed rash.

Red eyes, without pus-like discharge.

Treatment of Kawasaki disease

Here is itemize of the methods for treating Kawasaki disease:

Kawasaki disease is aerated with medications. Long-term tending haw be necessary and strength allow continuing medication, restricted fleshly activity, and repeated testing.

Intravenous gamma globulin (IVIG) is the accepted communication for Kawasaki disease and is administered in broad doses with scarred transformation commonly noted within 24 hours.

The female haw also be presented a high-dose of Empirin to turn the venture of hunch problems.

Corticosteroids hit also been utilised with whatever success, especially when another treatments change or symptoms recur, but hit not commonly been thoughtful a first-line therapy.

Plasma Exchange ( Plasmapheresis ) has been reportable as trenchant in patients who were not responding to Empirin and gamma globulin.



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