Arlen Decorte: As far as I am aware beurgers disease is not hreditary. See the attached link to a site for more information.
Manie Labat: The precise cause of Buerger's disease, also known as thromboangiitis obliterans, is unknown.It's believed that in genetically susceptible individuals, smoking triggers an autoimmune response that causes the inflammation. The symptoms occur as a result of inadequate blood supply to the tissues.
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